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Bettli Industry Limited

Levobupivacaine Hydrochloride, Levobupivacaine, Testosterone Undecanoate manufacturer / supplier in China, offering Levobupivacaine Hydrochloride Local Anesthetic Apis 99%, Anti Aging Durabolin/ Nandrolone Phenylpropionate / Npp Hormone Steroid for Muscle Building, Legit Steroid Raw Testosterone Propionate Powder 99% for Bodybuilding and so on.

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Supplier Homepage Product Local Anesthetic APIS Levobupivacaine Hydrochloride Local Anesthetic Apis 99%

Levobupivacaine Hydrochloride Local Anesthetic Apis 99%

FOB Price: US $1-6 / grams
Min. Order: 10 grams
Min. Order FOB Price
10 grams US $1-6/ grams
Get Latest Price
Port: Hong Kong, Hong Kong
Production Capacity: 500kg/Month
Payment Terms: T/T, Western Union, Paypal, Money Gram
Basic Info
  • Model NO.: 99
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • CAS No: 27262-48-2
  • M.W: 324.8887
  • Appearance: White Crystalline Powder
  • Transport Package: Very Discreet or as Required
  • Origin: China
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP, BP
  • State: Solid
  • Product Name: Levobupivacaine Hydrochloride
  • M.F: C18h29cln2o
  • Assays: 99%
  • Trademark: BETTLI
  • Specification: GMP, SGS, ISO, KOSHER
  • HS Code: 3001200020
Product Description
Levobupivacaine hydrochloride
Aust Prescr 2001;24:129-31
Chirocaine (Abbott) 
10 mL ampoules containing 2.5 mg/mL, 5 mg/mL and
7.5 mg/mL
Approved indication: anaesthesia
Australian Medicines Handbook Section 2.1
 
Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
 
The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
 
Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with fentanyl, morphine or clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
 
The adverse effects of the two drugs are also similar. They are influenced by how the drugs are administered, for example hypotension often occurs during epidural anaesthesia. Nausea and vomiting also occur commonly with both drugs.
 
To reduce adverse effects the smallest dose and concentration should be used. The 7.5 mg/mL concentration should not be used in children or in obstetrics. Like bupivacaine intravascular injection must be avoided, and levobupivacaine is contraindicated for intravenous regional anaesthesia (Bier's block) because of cardiotoxicity. It is also contraindicated as a paracervical block. Test doses with a short-acting local anaesthetic can be used before using levobupivacaine for a complete nerve block. Although animal studies suggest a benefit, it remains to be proven whether levobupivacaine has significantly less toxicity than bupivacaine.
 
Levobupivacaine Hydrochloride is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.
Local Anesthetic APIS
BenzocaineCAS: 94-09-7
Lidocaines HClCAS: 73-78-9
Procaine HClCAS: 51-05-8
Dyclonine HydrochlorideCAS: 536-43-6
Aarticaine HydrochlorideCAS: 23964-57-0
Propitocaine HydrochlorideCAS: 1786-81-8
Levobupivacaine HydrochlorideCAS: 27262-48-2
Ropivacaine MesylateCAS: 854056-07-8
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