99% Peptides 5mg/Vial Bodybuilding Sermorelin
|FOB Price:||US $1-9 / vials|
|Min. Order:||10 vials|
|Min. Order||FOB Price|
|10 vials||US $1-9/ vials|
|Payment Terms:||T/T, Paypal, Money Gram, Western Union, Bitcoin|
- Model NO.: 99
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Purity (by HPLC): 99.00%
- Usage: Releasing Hormone
- Packaging Details: Very Discreet
- Specification: 10mg/vial 10vials/kit
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- Product Name: Sermorelin
- Appearance: White Powder
- Minimum Order Quantity: 10vials
- Trademark: BETTLI
- Origin: China
Sermorelin is a hormone releasing hormone analogue. It is a 29-amino acid polypeptide representing the 1-29 fragment from endogenous human hormone releasing hormone, and is thought to be the shortest fully functional fragment of GHRH. Buy Sermorelin of high quality only at Superior Peptide.
|Unit size:||10 mg/vial|
|Physical State:||Lyophilized Powder|
|Solubility:||Soluble in water or 1% acetic acid|
|Storage:||Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.|
Sermorelin is a GHRH (hormone-releasing hormone) peptide analogue. Its peptide sequence is comprised of 29 amino acids. This sequence is a portion of the endogenous human GHRH, and is currently considered to be the shortest synthetic peptide that possesses the full array of functional GHRH activity. Due to this fact, sermorelin is considered to be a hormone secretagogue.
Sermorelin has been used during research to stimulate the secretion of growth hormone from the adenohypophysis (also called the anterior pituitary). The anterior pituitary secretes trophic hormones. Sermorelin has also been used in research stimulation tests to assess for pituitary sufficiency in relation to the secretion of the growth hormone.
GHRH is 44 amino-acids polypeptide that stimulates the secretion of hormone from the adenohypophysis. It is also called somatocrinin or somatoliberin. It is produced in the cell bodies of periventricular arcuate neurons, and thereafter transported to the neurosecretory terminals of the neurons where they are released. The arcuate neurons do form part of the hypothalamo-hypophyseal portal system. Their release from the neurosecretory terminals occur in a pulsatile fashion and it thus follows that hormone (GH) release also occurs in a corresponding pulsatile fashion. GHRH binds to a secretin-type G-protein coupled serpentine receptor called the GHRH-receptor (GHRHR). Binding causes the receptor to activate both the cAMP (cyclic Adenosine Monophosphate)-dependent pathway and the phospholipase C (PLC) pathway. The terminal downstream actions of the cAMP-dependent pathway do upregulate the transcription of both the GH and GHRHR genes thereby providing a positive feedback loop that amplifies the production of GH. The GH produced is thereafter packaged in secretory vesicles. The downstream actions of the PLC pathway results in both Na+-voltage-dependent and Ca2+-dependent fusion of the secretory vesicles with the plasma membrane thereby releasing GH into the bloodstream.
The actions of GH ensure an optimal well-regulated post-natal growth. GH also promotes efficient energy metabolism. Studies have also shown that GHRH directly promotes slow wave NREM (non-rapid eye movement) sleep, and thus GHRH insufficiency causes a reduction in the amount and intensity of slow wave NREM sleep which results in either insomnia or dysomnia (sleep disorders that causes sleep to lose its restorative capacity). Studies have also shown that GHRH inhibits the actions of somatostatin. Somatostatin is a polypeptide hormone that inhibits GH secretion from the adenohypophysis. Both GHRH and somatostatin are produced in the same neuron but they are released in alternation to each other thereby resulting in the pulsatile release of GH from the neuron.
Recent research has also shown that GHRH is also produced outside the hypothalamus by pancreatic cells, gastrointestinal tract epithelial cells and in some neoplastic cells. Clinical studies have also shown that the actions of Sermorelin are similar to the GHRH actions. Thus, Sermorelin has been used to diagnose deficiencies in GH secretions. Also, Sermorelin has been investigated for its therapeutic properties as the studies discussed below show.
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Shipping /return /refund policy
We will attempt to ship most orders within 48 hours excluding weekends or holidays.
International and EU orders ship via Priority mail or DHL based on weight. Customer will be provided with tracking number. Shipment to countries with tropical clima will be in isolated pack and with cooling inlets. After receiving all products must be placed into refrigeratot to +5° C.
All Items are shipped safely and in manner that ensures safe arrival. If for any reason this is not the case then please email us and we will work with you. Each case is handled individually.
We will accepts returns if it is due to damage that is our fault or manufacturers defects. The items that we sell are peptides and as such could degrade if improperly handled. As a result we are unable to resell products once they have left our warehouse. The return must be within 15 days of the time of the purchase.
Peptides on the other hand, due to their fragile nature and us being to monitor how they were handled when they were out of care, could possibly degrade. We prefer not to accept returns of peptides due to this fact.
If you are missing an item or the item you receive is damaged, then please contact us and we will sent out a replacement free of shiping cost to you.