99% Local Anesthetic Drug Lidocaine Hydrochloride CAS: 73-78-9
|FOB Price:||US $1-6 / grams|
|Min. Order:||1 grams|
|Min. Order||FOB Price|
|1 grams||US $1-6/ grams|
|Port:||Hong Kong, Hong Kong|
|Payment Terms:||T/T, Western Union, Paypal, Money Gram, Bitcoin|
- Model NO.: 20
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- M.F.: C14h23cln2o
- Assays: 99%
- Transport Package: 25kg/Drum
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- CAS No: 73-78-9
- M.W.: 270.7982
- Trademark: BETTLI
- Specification: 99
- HS Code: 3001200020
Tetracaine /Benzocaine /Lidocaine HCl /Lidocaine Hydrochloride
Product name: Lidocaine Hydrochloride
CAS Registry Number: 73-78-9
Qualitity Standard: CP2005;BP2003
Appearance: White crystalline powder
Lidocaine may be absorbed following topical administration to mucous membranes, its rate and extent of absorption depending upon concentration and total dose administered, the specific site of application, and duration of exposure. In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. Lidocaine is also well-absorbed from the gastrointestinal tract, but little intact drug may appear in the circulation because of biotransformation in the liver.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide.
The plasma binding of lidocaine is dependent on drug concentration, and the fraction bound decreases with increasing concentration. At concentrations of 1 to 4 mcg of free base per mL, 60 to 80 percent of lidocaine is protein bound. Binding is also dependent on the plasma concentration of the alpha-1-acid glycoprotein.
Lidocaine, usually in the form of lidocaine hydrochloride, is available in various forms including:
Injected local anesthetic (sometimes combined with epinephrine to reduce bleeding)
Dermal patch (sometimes combined with prilocaine)
Nasal instillation/spray (combined with phenylephrine)
Oral gel (often referred to as "viscous lidocaine" or abbreviated "lidocaine visc" or "lidocaine HCl visc" in pharmacology; used as teething gel)
Oral and topical ointments, with and without flavoring, respectively
Topical gel (as with aloe vera gels that include lidocaine)
Lidocaine HCl 2% jelly, combined with hypromellose, to anesthetize and lubricate the urethra, etc., for inserting a catheter or instrument
Topical patch (lidocaine 5%), marketed since 1999 in the US by Endo Pharmaceuticals as "Lidoderm" - and since 2007 in the UK by Grünenthal as "Versatis".
Topical ointment (lidocaine 5%) as a temporary reliever of discomfort associated anorectal disorders, such as hemorrhoids, marketed as an over-the-counter product in the US as RectiCare since 2012 by Ferndale Healthcare, Inc
Topical aerosol spray
Inhaled by nebulizer
As a component of a GI cocktail used in emergency rooms
This medication is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area (e.g., anal fissures, itching around the vagina/rectum). Some forms of this medication are also used to decrease discomfort or pain during certain medical procedures/exams (e.g., sigmoidoscopy, cystoscopy). Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.
|Product name||Lidocaine Hydrochloride|
|Appearance||White crystalline powder|
|Assay (C13H20N2O2·HCl)||99.0% to 101.0%||99.75%|
|Solution Appearance||Clear and colorless||Confirm|
|Related impurities||impurity A:≤0.01%||0.002%|
|Single unspecified impurity: ≤0.1%||0.02%|
|Total impurity: ≤0.5%||0.20%|
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