Gold Member Since 2016
Bettli Industry Limited

Aicar, Test E, Mk-677 (Ibutamoren) manufacturer / supplier in China, offering Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment, Melanotan 2 Injections Hormone Peptide Mt2 Tanning Injections Wholesale Price, Wholesale Peptide Melanotan 2 Injections Mt2 Skin Tanning Injections and so on.

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Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment

FOB Price: US $1-6 / grams
Min. Order: 10 grams
Min. Order FOB Price
10 grams US $1-6/ grams
Get Latest Price
Port: Hong Kong, Hong Kong
Production Capacity: 500kg/Month
Payment Terms: T/T, Western Union, Paypal, Money Gram
Basic Info
  • Model NO.: 99
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • CAS No: 317318-70-0
  • M.W: 453.50
  • Appearance: White Fine Powder
  • Transport Package: Very Discreet or as Required
  • Origin: China
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP, BP
  • State: Solid
  • Product Name: Gw-501516
  • M.F: C21h20f3no3s2
  • Assays: 99%
  • Trademark: BETTLI
  • Specification: GMP, SGS, ISO, KOSHER
  • HS Code: 3001200020
Product Description
Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment
Product Details
Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 99%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFKB and C/EBP pathways.

Specification:
ItemSpecificationResult
AppearanceWhite powderComplies
Related substance (HPLC)Total impurity ≤0.5%
Max single impurity ≤0.1%
0.2%
0.06%
OdorCharacteristicComplies
Assay99%99.8%
Sieve analysis100% pass 80 meshComplies
Loss on Drying
Residue on Ignition
≤1.0%
≤1.0%
0.12%
0.09%
Heavy Metal<10ppmComplies
As<0.1ppm0.05ppm
Pb<0.1ppm0.05ppm
Cd<0.1ppm0.05ppm
Residual Solvents<100ppmComplies
Residual PesticideNegativeComplies
Microbiology  
Total Plate Count<1000cfu/gComplies
Yeast & Mold<100cfu/gComplies
E.ColiNegativeComplies
SalmonellaNegativeComplies
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