White Crystalline Powder L (-) -Epinephrine Supplie Pharmaceutical Intermediate
|FOB Price:||US $1-5 / grams|
|Min. Order:||10 grams|
|Min. Order||FOB Price|
|10 grams||US $1-5/ grams|
|Payment Terms:||T/T, Western Union, Paypal, Money Gram|
- Model NO.: 99
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- M.F.: C9h13no3
- Reference Standard: USP30
- Transport Package: Foil Bag or Other Packagings
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- CAS: 51-43-4
- M.W.: 183.2
- Trademark: BETTLI
- Specification: 1kg/bag
- HS Code: 3002100000
Product name: L(-)-Epinephrine
L(-)-Epinephrine Synonyms: (R) - epinephrine; 1- (3,4-dihydroxyphenyl) -2-aminoethanol; 3,4-dihydroxy -α- (methylaminomethyl) benzyl alcohol; adrenal base ; adrenalin; adrenalin; L-3,4- dihydroxy -alpha - ((methylamino) methyl) benzyl alcohol; L- epinephrine
L(-)-Epinephrine English name: L (-) - Epinephrine
L(-)-Epinephrine Synonyms: (-) - epinephrine [qr]; (R) -4- [1-Hydroxy-2- (methylamino) ethyl] -1,2-benzenediol; (r) -epinephrine [qr]; 1,2- Benzenediol, 4- [1-hydroxy-2- (methylamino) ethyl] -, (R) -; 1,2-Benzenediol, 4- [1-hydroxy-2- (methylamino) ethyl] -, (R) -; 1-1- (3,4-dihydroxyphenyl) -2-methylaminoethanol [qr]; 1-adrenalin [qr]; 1-Adrenalin
L(-)-Epinephrine CAS: 51-43-4
Molecular Weight: 183.2
EINECS Number: 200-098-7
melting point:215 ° C (dec.) (Lit.)
Specific rotation:-51.5° (c = 4, 1M HCl, dry sub)
Refractive index :-51.5 °(C = 4, 1mol / L HCl)
Storage :2-8 °C
Water solubility: <0.01 g / 100 mL at 18 oC
L(-)-Epinephrine Appearance: white crystalline powder.
Solubility: soluble in mineral acids and alkali hydroxide solution, slightly soluble in water, soluble in alcohol, ether, acetone, chloroform. Odorless, bitter taste. Exposed in the air and see the light color gradually deep.
Summary: epinephrine (adrenalin, epinephrine, capital abbreviations are: A or E) is the main hormone of the adrenal medulla, the biosynthesis mainly in the medulla chromaffin cells norepinephrine first formed, then further through phenethylamine -N- methyl transferase (phenylethanolamine N-methyl transferase, PNMT) the role of the norepinephrine methylated form of adrenalin.
L(-)-Epinephrine Usage: non-steroidal hormone drugs, also used as a hemostatic Adrenosem intermediates. Mainly used for anaphylactic shock, bronchial asthma and cardiac arrest rescue. The main clinical use of cardiac arrest, bronchial asthma, anaphylactic shock, but also treat hives, hay fever and nasal or gum bleeding.
Mechanism: the direct effect of the product on the adrenergic α, β receptors, resulting in rapid and brief strong excitement α and β-type effect on the heart β1- receptors excited, can enhance myocardial contractility, heart rate, cardiac increased oxygen consumption. At the same effect on vascular smooth muscle β2- receptor, blood vessels dilate, reduce peripheral vascular resistance and reduced diastolic blood pressure. Β2- excited receptors in bronchial smooth muscle relaxation, bronchodilation, relieve bronchial spasm; for α- receptor stimulant, the skin, mucosal vascular and visceral small blood vessels.
|Characters||White or greyish-white crystalline odorless soluble||greyish-white crystalline|
|powder,freely soluble in acid water,slightly||odorless powder|
|in alcohol ,practically insoluble in ether.|
|Identificaion||0.10N iodine deep red color||validity|
|Specific rotaion||Between -50.0°and -53.5°||-51.0°|
|Loss on drying||Not more than 2.0%||0.5%|
|Residue on lgnition||Negligible||Negligible|
|Limit of adrenalone||At 310 nm not more than 0.20||0.027|
|Limit of noreponephrine||Not more than 4.0%||1.0%|
|Assay||Not less than 97.0% and not more than 102.0%||99.9%|
|Residula solvents||Methanol: not more than 3000ppm||Methanol:1500ppm|
|Storage||Store in vacuum and protected from light|
|CONCLUSION:||The above product complies with the standard of contract. UPS32|
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