Procaine Hcl Crystalline Powder Procaine Hydrochloride Local Anesthetic Procaine
Procaine hydrochloride, also called Novocain, or Novocaine, synthetic organic compound used in medicine as a local anesthetic. Introduced in 1905 under the trade name Novocaine, it became the first and best-known substitute for cocaine in local anesthesia. Generally used in a 1 to 10 percent saline solution, procaine hydrochloride is administered by injection for infiltration (area flooding as in dental anesthesia), nerve-block, spinal, and caudal anesthesia. Unlike cocaine, procaine is not toxic, addicting, or irritating. It has been displaced somewhat by the chemically related drugs lidocaine and mepivacaine, which produce prompter, more intense anesthesia.
Procaine Hydrochloride Usage
Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically . It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine Hydrochloride Description
Procaine HCL is actually a very simple combination of two B vitamins, PAPA (P-aminobenzoic acid) and DEAE (diethylaminoethanol) buffered and stabilized with benzoic acid and potassium metabisulfite for more effectiveness inside the body. Procaine hydrochloride is a compound combination of PABA and DEAE, a vitaminic substance first synthesized in 1905 by a German chemist, Dr. Albert Einhorn, who was looking for a simple, non-addictive anesthetic.
For years procaine was used as a simple anesthetic, but soon researchers began to notice other curative powers of this substance. Interest in experimentation ran so high that between 1930 and 1951, over 165 reports were published on the effects of procaine in the treatment of a variety of conditions including arthritis, neuralgia, itching, peptic ulcer, asthma and hypertension. In the late 1940's three French physicians - Drs. Ghali, Boudon, and Guoit - found that procaine hydrochloride helped relieve suffering from asthma attacks. Dr. Rene Leriche discovered that procaine injections were helpful in treating certain forms of arthritis, arteritis, and blood clots in the limbs.
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